Skip Navigation LinksCore Service > Lab Test Directory > Biochemistry > Details

Core Services Test Directory

Go to all departments

Molybdenum - 24hr Urine

Container:

Molybdenum - 24hr Urine
Click here to magnify the image.

Reference Range:

114.7 - 917.2 nmol/24hr

Turnaround Time:

5 Days

Description:

Molybdenum - 24hr Urine

Preparation:

Must use acid washed bottle

Vessels and Containers:

20ml Sterile Universal Container

Important Information:

Molybdenum is used in many industrial processes, mainly as a component of stainless steels and other alloys. It is used in the chromium-cobalt alloy used for orthopaedic implants.

Biological Function
Molybdenum is an essential trace element and has several functions. In bacteria it is a component of several nitrogenases. In animals it is a cofactor of xanthine oxidase, metabolising xanthine to uric acid. The most important role is a molybdenum cofactor, a complex of molybdopterin with molybdenum, which is essential for sulphite oxidase, xanthine oxidoreductase and aldehyde oxidase. Molybdenum cofactor deficiency can cause severe neurological abnormalities and death. Deficiency cannot be detected by measuring molybdenum concentrations.

Deficiency
Molybdenum deficiency is rare in most populations, but there are parts of the world with low endogenous molybdenum intake and reduced intake has been associated with oesophageal cancer in China. There have been rare reports of molybdenum deficiency associated with TPN, with increased concentrations of sulphite and urate.

Toxicity
High concentrations of molybdenum will interfere with copper absorption and metabolism and can cause copper deficiency. Tetrathiomolybdate is used as a treatment for Wilson’s Disease. Exposure to molybdenum dust can cause irritation to eyes, sinuses and skin.

Laboratory measurements
Molybdenum can be measured in blood, serum or urine. Apart from occupational exposure there are few indications for measuring molybdenum concentrations. There is no value in measuring molybdenum in patients with orthopaedic implants.

Transportation and Handling:

Send by 1st Class Post

Time limits for requesting additional examinations:

Upto 2 weeks post original request